Autoimmunity: Criteria for autoimmunity, Classifications of autoimmune diseases in man, mechanism of autoimmunity, Transplantation and immunologic tolerance, allograft rejections, transplantation antigens, mechanism of rejection of allograft

Curriculum Unit: 3. Diseases of Immunity:

This study module covers "Autoimmunity: Criteria for autoimmunity, Classifications of autoimmune diseases in man, mechanism of autoimmunity, Transplantation and immunologic tolerance, allograft rejections, transplantation antigens, mechanism of rejection of allograft", an integral component of the Year 2 Doctor of Pharmacy (Pharm.D) curriculum under Pathophysiology (Diseases of Immunity). Designed for clinical pharmacy scholars, the syllabus emphasizes mechanistic understanding, clinical relevance, and high-yield examination competencies.

Upon reviewing this syllabus topic, Pharm.D students are expected to demonstrate proficiency in:

• Understand the foundational etiology, classification, and clinical significance of Autoimmunity: Criteria for autoimmunity, Classifications of autoimmune diseases in man, mechanism of autoimmunity, Transplantation and immunologic tolerance, allograft rejections, transplantation antigens, mechanism of rejection of allograft.
• Analyze the underlying pathophysiology and disease manifestations relevant to Diseases of Immunity.
• Evaluate evidence-based pharmacotherapeutic management, therapeutic drug choices, and dosage individualization.
• Identify critical patient monitoring parameters, adverse drug reactions (ADRs), and drug-drug interactions.

Standard literature and institutional sources for Pathophysiology:

• [1]Pharmacy Council of India (PCI) Pharm.D Curriculum Syllabus Guidelines
• [2]Robbins & Cotran Pathologic Basis of Disease (Kumar, Abbas, Aster)
• [3]Pathophysiology of Disease: An Introduction to Clinical Medicine (Hammer & McPhee)